| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | BFPP; BPPR; GPR56; TM7LN4; TM7XN1 |
| Description | Human ADGRG1 full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | Q9Y653 |
| Expression Host | HEK293 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | N.A. |
| Molecular Weight | The human full length ADGRG1 protein has a MW of 77.7 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | A member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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