| Target | |
|---|---|
| Synonyms | Adhesion G protein-coupled receptor E2;EGF-like module receptor 2;EGF-like module-containing mucin-like hormone receptor-like 2;CD312 |
| Description | Recombinant human ADGRE2 protein with C-terminal 7×His tag |
| Delivery | In Stock |
| Uniprot ID | Q9UHX3 |
| Expression Host | HEK293 |
| Tag | C-7×His Tag |
| Molecular Characterization | ADGRE2(Gln24-Thr537) 7×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 57.2 kDa after removal of the signal peptide. The apparent molecular mass of ADGRE2-His is approximately 70-100 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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