| Clone ID | 1A12 |
|---|---|
| Target | |
| Synonyms | Interleukin-31;IL-31 |
| Host Species | Rabbit |
| Description | Anti-IL31 antibody(1A12), IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | Q6EBC2 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA |
| Recommended Dilutions | ELISA 1/5000-10000 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Powder |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
| Background | IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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