Clone ID | 13D3 |
---|---|
Target | |
Synonyms | ERBB3; FERLK; LCCS2; VSCN1; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3 |
Host Species | Rabbit |
Description | Anti-Her3 antibody(13D3), Rabbit mAb |
Delivery | In Stock |
Uniprot ID | P21860 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | WB |
Recommended Dilutions | WB 1:1000 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
Usage | Research use only |
Anti-Her3 antibody(13D3), Rabbit mAb
Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
Product Data
图片
Figure 1.Anti-Her3 antibody (SKU# DME100433) at 1/1000 dilution
Lane : Huh7, whole cell lysate
Secondary : Goat Anti-Rabbit IgG H&L (HRP) at 1/5000 dilution
Predicted band size: 148 kDa
Observed band size: 105,260 kDa
相关产品
ECD Proteins
SKU: PME101411 Target: HER3
Price: 10μg ¥600.00 ; 50μg ¥2199.00 ; 100μg ¥3299.00
Monoclonal Antibodies
SKU: DME100580 Target: HER3
Application: IHC; Flow Cyt
Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
Biosimilar reference antibodies
SKU: BME100057B Target: HER3
Application: ELISA; Flow Cyt
Price: 50 μg ¥890.00 ; 100 μg ¥1699.00
DiSliceX
SKU: SLI100007 Target: CD46, CD73, CDH17, CEACAM5, EPCAM, FZD10, GPA33, GUCY2C, HER3
Application: IHC
Price: 2 slides ¥899.00
Overexpression Stable Cell Line
SKU: CEL100032 Target: HER3
Application: FACS Data
Price: Inquiry