Clone ID | DM208 |
---|---|
Target | |
Synonyms | CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR |
Host Species | Rabbit |
Description | Anti-CXCR3 antibody(DM208); Rabbit mAb |
Delivery | In Stock |
Uniprot ID | P49682 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes a G protein-coupled receptor with selectivity for three chemokines; termed CXCL9:Mig (monokine induced by interferon-g); CXCL10:IP10 (interferon-g-inducible 10 kDa protein) and CXCL11:I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic; most notably integrin activation; cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine; CXCL4:PF4 (PMID:12782716). [provided by RefSeq; Jun 2011] |
Usage | Research use only |
Conjugate | Unconjugated |
Anti-CXCR3 antibody(DM208); Rabbit mAb
Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
Product Data
图片
Figure 1. Flow cytometry analysis with Anti-CXCR3 (DM208) on Expi293 cells transfected with human CXCR3 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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