| Target | |
|---|---|
| Synonyms | CD267;TACI;TNFRSF13B |
| Description | Recombinant human TACI Protein with C-terminal Human Fc tag |
| Delivery | In Stock |
| Uniprot ID | O14836 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | TACI(Ser2-Ser165) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 44.5 kDa after removal of the signal peptide.The apparent molecular mass of TACI-hFc is approximately 33-53 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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