| Clone ID | 6A7 |
|---|---|
| Target | |
| Synonyms | VGR;VGR1 |
| Host Species | Rabbit |
| Description | Anti-BMP6 antibody(6A7), IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P22004 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA |
| Recommended Dilutions | ELISA 1:5000-10000 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Endotoxin | Less than 1.0 EU/μg by the LAL method. For <1 EU/mg requirements, please contact us for customization. |
| Formulation & Reconstitution | Powder |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 μm) prior to use. |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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