| Target | |
|---|---|
| Synonyms | ALXDRD |
| Description | Recombinant human GFAP(68-377) protein with N-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | P14136 |
| Expression Host | HEK293 |
| Tag | N-6×His Tag |
| Molecular Characterization | 6×His tag GFAP(Ser68-Ile377) |
| Molecular Weight | The protein has a predicted molecular mass of 37.2 kDa after removal of the signal peptide. The apparent molecular mass of His-GFAP(68-377) is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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