| Target | |
|---|---|
| Synonyms | Ptprc;B220;L-CA;Ly-5;T200;CD45R;Lyt-4 |
| Description | Recombinant mouse CD45 protein with C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | P06800 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | Mouse CD45(Gln26-Lys566) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 59.5 kDa after removal of the signal peptide. The apparent molecular mass of mCD45-His is approximately 130-250 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C). [provided by Alliance of Genome Resources, Apr 2022] |
| Usage | Research use only |
Mouse CD45 Protein, His Tag
Price: 10μg ￥690.00 ; 50μg ￥2500.00 ; 100μg ￥3699.00
Product Data
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Figure 1. Mouse CD45 Protein, His Tag on SDS-PAGE under reducing condition.