| Target | |
|---|---|
| Synonyms | CD2, Cd2, LFA-2, LFA2, Ly37, Ly-37, CD2 Antigen, T-Cell Surface Antigen CD2, Lymphocyte Function-Associated Antigen 2 |
| Description | Recombinant mouse CD2 protein with C-terminal 10×His tag |
| Delivery | In STOCK |
| Uniprot ID | P08920 |
| Expression Host | HEK293 |
| Tag | C-10×His tag |
| Molecular Characterization | Mouse CD2(Arg23-Ser203)+10×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 22.1 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Background | CD2 is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is primarily expressed on T lymphocytes, natural killer cells, and thymocytes. In mice, CD2 interacts with CD48 and promotes immune-cell adhesion, immunological synapse formation, and antigen recognition. CD2 also functions as a costimulatory receptor that regulates T-cell and natural killer cell activation, proliferation, cytokine production, and cytotoxic activity. Mouse CD2 is widely used as a lymphocyte marker and is an important target for immunology, inflammation, transplantation, and therapeutic antibody research. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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