| Tag | N-His, C-Strep Tag |
|---|---|
| Expression Host | E.coli |
| Target | |
| Description | Human STEAP1 cell-free full length protein-Nanodisc |
| Synonyms | PRSS24; STEAP |
| Uniprot ID | Q9UHE8 |
| Protein Families | Transmembrane |
| Protein Pathways | N/A |
| Molecular Weight | The human STEAP1 cell-free full length protein-Nanodisc has a MW of 43.9kDa |
| Delivery | 1 week |
| Formulation & Reconstitution | Liquid, 50mM HEPES, 150mM NaCl, pH7.5 |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Storage&Shipping | Store at -80℃, Ship on dry ice. |
| Purity | >80% |
| Background | STEAP1 is a cell-surface biomolecule composed by sixtransmembrane domains connected by intra- and extracellular loops. It is commonly found overexpressed in several types of cancers, namely in PCa, and is preferentially located at the tight or gap junctions. However, in nontumoural tissues and vital organs, STEAP1 protein presents low or absent expression, unveiling considerable specificity for cancer environment. Taking into account STEAP1 predicted transmembrane topology and cellular localization, it has been hypothesized that STEAP1 may play an important role as a transporter protein and can be involved in intercellular communication. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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