Target | |
---|---|
Synonyms | R-spondin-1;hRspo1 |
Description | Recombinant human RSPO1(21-263) protein with C-terminal 6×His tag |
Delivery | In Stock |
Uniprot ID | Q2MKA7 |
Expression Host | HEK293 |
Tag | C-6×His Tag |
Molecular Characterization | RSPO1(Ser21-Ala263) 6×His tag |
Molecular Weight | The protein has a predicted molecular mass of 27.6 kDa after removal of the signal peptide. The apparent molecular mass of RSPO1(21-263)-His is approximately 35-55 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Usage | Research use only |
Human RSPO1(21-263) Protein, His Tag
Price: 10μg ¥727.00 ; 50μg ¥2700.00 ; 100 μg ¥3999.00
Product Data
图片
Figure 1. Human RSPO1(21-263) Protein, His Tag on SDS-PAGE under reducing condition.
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