| Target | |
|---|---|
| Synonyms | C7orf15;CD112R |
| Description | Recombinant human PVRIG protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q6DKI7 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | PVRIG(Met1-Thr25 Pro80-Ala170) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 38.2 kDa after removal of the signal peptide.The apparent molecular mass of PVRIG-hFc is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.[UniProtKB/Swiss-Prot Function] |
| Usage | Research use only |
| Conjugate | Unconjugated |
服务热线
400-006-0995
18062749453
