Recombinant human PD-1 protein with C-terminal 6×His tag
PD-1(Leu25-Gln167) 6×His tag
The protein has a predicted molecular mass of 16.8 kDa after removal of the signal peptide.
The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Research use only
Human PD-1 Protein, His tag
Price: 10μg ￥636.00 ; 50μg ￥2333.00 ; 100 μg ￥3499.00
Figure 1. Human PD-1 Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well)Human PD-1 Protein,His tag (PME100461) can bind Anti-PD-1 antibody(DM177), Rabbit mAb in a linear range of 0.06–1.60 ng/mL.