| Target | |
|---|---|
| Synonyms | Olfactory receptor OR1‑57; Olfactory receptor family 2 subfamily T member 12 |
| Description | Recombinant human OR2T12 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q8NG77 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | OR2T12(Met1-Gln23) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 28.9 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | OR2T12 encodes an olfactory receptor that belongs to the G-protein coupled receptor (GPCR) superfamily and is part of the large olfactory receptor gene family responsible for odor recognition. OR2T12 is expressed in the olfactory epithelium, where it binds specific odorant molecules and couples to G olf proteins to activate adenylyl cyclase, increase cAMP, and trigger neuronal depolarization for smell perception. Like other olfactory receptors, OR2T12 is a single-exon gene encoding a 7-transmembrane domain protein. Emerging studies suggest that some olfactory receptors, including OR2T12, may also be expressed in non-olfactory tissues, potentially participating in cell signaling and chemosensory responses outside the nasal cavity. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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