| Target | |
|---|---|
| Synonyms | IL-20;Cytokine Zcyto10 |
| Description | Recombinant human IL20 Protein with C-terminal Human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q9NYY1 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | IL20(Leu25-Glu176) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 43.7 kDa after removal of the signal peptide. The apparent molecular mass of IL20-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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