| Target | |
|---|---|
| Synonyms | DIAR6;GC-C;GUC2C;MECIL;MUCIL;STAR |
| Description | Recombinant human GUCY2C protein with C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | P25092 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | GUCY2C(Ser24-Gln430) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of GUCY2C-His is approximately 55-130 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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