| Tag | N-Single Strep, C-Flag Tag |
|---|---|
| Expression Host | E.coli |
| Target | |
| Description | Human CXCR4 cell-free full length protein-Nanodisc |
| Synonyms | CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS |
| Uniprot ID | P61073 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane |
| Protein Pathways | Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Leukocyte transendothelial migration |
| Molecular Weight | The human CXCR4 cell-free full length protein-Nanodisc has a MW of 42.1kDa |
| Delivery | 1 week |
| Formulation & Reconstitution | Liquid, 20mM HEPES, 150mM NaCl, pH8.5 |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Storage&Shipping | Store at -80℃, Ship on dry ice. |
| Purity | >80% |
| Background | A CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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