| Target | |
|---|---|
| Synonyms | NG2; MCSP; MCSPG; MSK16; CSPG4A; HMW-MAA; MEL-CSPG |
| Description | Recombinant human CSPG4(1538-2221) Protein with C-terminal mouse Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q6UVK1 |
| Expression Host | HEK293 |
| Tag | C-mouse Fc tag |
| Molecular Characterization | CSPG4(Gln1538-Asn2221) mFc(Pro99-Lys330) |
| Molecular Weight | The protein has a predicted molecular mass of 99.0 kDa after removal of the signal peptide. The apparent molecular mass of CSPG4(1538-2221)-mFc is approximately 130-250 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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