| Target | |
|---|---|
| Synonyms | MED; CTS2; EDM1; EPD1; TSP5; PSACH; THBS5; TSP-5 |
| Description | Recombinant human COMP Protein with C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | P49747 |
| Expression Host | HEK293 |
| Tag | C-6×His tag |
| Molecular Characterization | COMP(Gln21-Ala757) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 81.8 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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