| Target | |
|---|---|
| Synonyms | p67; SIGLEC3; SIGLEC-3 |
| Description | Recombinant human CD33(18-259) Protein with C-terminal 10×His tag |
| Delivery | In Stock |
| Uniprot ID | P20138 |
| Expression Host | HEK293 |
| Tag | C-10×His tag |
| Molecular Characterization | CD33(Asp18-His259) 10×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 28.2 kDa after removal of the signal peptide. The apparent molecular mass of CD33(18-259)-His is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2022] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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