| Target | |
|---|---|
| Synonyms | B7-H5;B7H5;C10orf54;DD1alpha;Dies1;GI24;PD-1H;PP2135;SISP1;VISTA |
| Description | Recombinant Human B7-H5 with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q9H7M9 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | B7-H5(Phe33-Ala194) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of B7-H5-hFc is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777).[UniProtKB/Swiss-Prot Function] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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