| Target | |
|---|---|
| Synonyms | Midkine |
| Description | Recombinant Cynomolgus MDK protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | A0A2K5UAU4 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | MDK(Lys23-Asp143) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 39.4 kDa after removal of the signal peptide. The apparent molecular mass of cMDK-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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