| Common Name | UC-961,cirmtuzumab |
|---|---|
| Conjugate | Unconjugated |
| Synonyms | ROR1;NTRKR1 |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Humanized |
| IgG type | Human IgG1 – kappa |
| Reactivity | Human |
| Target | |
| Uniprot ID | Q01973 |
| Description | Anti-ROR1 (zilovertamab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
Anti-ROR1 (zilovertamab biosimilar) mAb
Price:50 μg ￥800.00 ; 100 μg ￥1500.00
Product Data Dima FAQ
图片 Dima FAQ
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human ROR1, His tagged protein PME100399 can bind Anti-ROR1 Neutralizing antibody (BME100073) in a linear range of 0.64-16 μg/ml.
Figure 2. Flow cytometry analysis with Anti-ROR1 (zilovertamab biosimilar) mAb 15 μg/mL on HEK293 cells transfected with Human ROR1 (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).
Figure 3. Flow cytometry analysis of antigen binding of anti-human ROR1 mAb(BME100073).
(A) A clear peak shift of BME100073 was seen compared to the control when incubated with ROR1-expressing 8226 cells, indicating strong binding of BME100073 to ROR1. Antibodies were incubated at 2 μg/mL.
Figure 4. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human ROR1(30-164) Protein, hFc Tag (PME101581) can bind Anti-ROR1 (zilovertamab biosimilar) mAb (BME100073) in a linear range of 40–200 ng/mL. In order to specifically detect BME100073, mouse anti-human Fab-specific antibody was used as detection antibody.
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