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SARS-CoV-2 (Omicron) S protein RBD, hFc Tag

产品概述
Catalog Number PME100687
Package 10 μg ¥600.00 ; 50 μg ¥2400.00 ; 100 μg ¥3600.00
Description Recombinant SARS-CoV-2 RBD(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) protein with C-terminal human Fc tag
Synonyms SARS-CoV-2 B.1.1.529 (Omicron) Spike RBD Protein
Delivery In Stock
Uniprot ID P0DTC2
Expression Host HEK293
Tag C-Human Fc tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 51.2 kDa after removal of the signal peptide.The apparent molecular mass of RBD(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H)-hFc is approximately 55-70 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage Store at -20°C to -70°C for 12 months in lyophilized state
Usage Research use only
Images

这里上传图片

Figure 1. SARS-CoV-2 (2019-nCoV) S protein RBD (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H), hFc Tag on SDS-PAGE under reducing condition.

Background SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.
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