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Human FAP(30-760) Protein, His Tag

产品概述
Catalog Number PME100626
Package 10 μg ¥600.00 ; 50 μg ¥2300.00 ; 100 μg ¥3400.00
Description Recombinant human FAP(30-760) protein with C-terminal 6×His tag
Synonyms FAP,FAPalpha,SIMP,Seprase,APCE
Delivery In Stock
Uniprot ID Q12884
Expression Host HEK293
Tag N-6×His tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 85.4 kDa after removal of the signal peptide. The apparent molecular mass of His-FAP(30-760) is approximately 100-130 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage Store at -20°C to -70°C for 12 months in lyophilized state
Usage Research use only
Images

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Figure 1. Human FAP(30-760) Protein, His Tag on SDS-PAGE under reducing condition.

Background The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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