| Target | |
|---|---|
| Synonyms | CD66b;CD67;CGM6;NCA-95 | 
| Description | Recombinant human CEACAM8 protein with C-terminal 6×His tag | 
| Delivery | In Stock | 
| Uniprot ID | P31997 | 
| Expression Host | HEK293 | 
| Tag | C-6×His Tag | 
| Molecular Characterization | CEACAM8(Gln35-Ser319) 6×His tag | 
| Molecular Weight | The protein has a predicted molecular mass of 32.2 kDa after removal of the signal peptide. The apparent molecular mass of CEACAM8-His is approximately 35-70 kDa due to glycosylation. | 
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. | 
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. | 
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | 
| Background | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764).[UniProtKB/Swiss-Prot Function] | 
| Usage | Research use only | 
| Conjugate | Unconjugated | 
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