| Target | |
|---|---|
| Synonyms | CD226;PTA1 |
| Description | Recombinant mouse DNAM-1 protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q5DW69 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | Mouse DNAM-1(Glu19-Pro254) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 52.9 kDa after removal of the signal peptide. The apparent molecular mass of mDNAM-1-hFc is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.[UniProtKB/Swiss-Prot Function] |
| Usage | Research use only |
| Conjugate | Unconjugated |
服务热线
400-006-0995
18062749453
