| Target | |
|---|---|
| Synonyms | CD127, CDW127, IL-7R-alpha, IL7RA, ILRA |
| Description | Recombinant human IL7RA with C-terminal human Fc Avi tag |
| Delivery | In STOCK |
| Uniprot ID | P16871 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Avi tag |
| Molecular Characterization | IL7RA(Glu21-Gly236)+hFc(Glu99-Ala330)+Avi tag |
| Molecular Weight | The protein has a predicted molecular mass of 52.8 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Background | The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015] |
| Usage | Research use only |
| Conjugate | Biotinylated |
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