| Target | |
|---|---|
| Synonyms | HCR, CKRX, CRAM, ACKR5, CRAM-A, CRAM-B |
| Description | Recombinant human CCRL2 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | O00421 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | CCRL2(Met1-Gln39) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 30.5 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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