| Target | |
|---|---|
| Synonyms | ACTHR |
| Description | Recombinant human MC2R Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q01718 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | MC2R(Met1-Arg23) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 28.8 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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