| Target | |
|---|---|
| Synonyms | P80; IL1R; CRMO3; IL1R1; CD121A; D2S1473; IL-1RT1; IL-1R-alpha |
| Description | Recombinant human IL1RA Protein with C-terminal mouse Fc tag |
| Delivery | In Stock |
| Uniprot ID | P14778 |
| Expression Host | HEK293 |
| Tag | C-mouse Fc tag |
| Molecular Characterization | IL1RA(Leu18-Thr332) mFc(Pro99-Lys330) |
| Molecular Weight | The protein has a predicted molecular mass of 62.4 kDa after removal of the signal peptide. The apparent molecular mass of IL1RA-mFc is approximately 70-100 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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