| Target | |
|---|---|
| Synonyms | GPR5; CCXCR1 |
| Description | Recombinant human XCR1 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P46094 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | XCR1(Met1-Thr31) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 29.7 kDa after removal of the signal peptide. The apparent molecular mass of XCR1-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains. The encoded protein transduces a signal by increasing the intracellular calcium ion level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Some studies have implicated a cluster of genes at 3p21.31, including this gene, as associated with COVID-19 risk. The encoded protein may also play a role in cell proliferation and migration in several types of cancer. [provided by RefSeq, Jan 2023] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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