| Target | |
|---|---|
| Synonyms | SIGLEC2; SIGLEC-2 |
| Description | Recombinant human CD22(417-678) Protein with C-terminal mouse Fc tag |
| Delivery | In Stock |
| Uniprot ID | P20273 |
| Expression Host | HEK293 |
| Tag | C-mouse Fc tag |
| Molecular Characterization | CD22(Tyr417-Tyr678) mFc(Pro99-Lys330) |
| Molecular Weight | The protein has a predicted molecular mass of 55.5 kDa after removal of the signal peptide. The apparent molecular mass of CD22(417-678)-mFc is approximately 70-100 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. [provided by Alliance of Genome Resources, Apr 2022] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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