Target | |
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Synonyms | CANN6;CB-R;CB1;CB1A;CB1K5;CB1R;CNR |
Description | Recombinant Human CB1 protein with C-terminal human Fc |
Delivery | In Stock |
Uniprot ID | P21554 |
Expression Host | HEK293 |
Tag | C-Human Fc Tag |
Molecular Characterization | CB1(Met1-Gln116) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide.The apparent molecular mass of CB1-hFc is approximately 55-70 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. |
Usage | Research use only |
Conjugate | Unconjugated |
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