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Human GPRC5D full length protein-synthetic nanodisc

产品概述
Catalog Number FLP100011
package 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00
Description Human GPRC5D full length protein-synthetic nanodisc
Expression Host HEK293
Symbol GPRC5D
ORF Size 1035 bp
Formulation Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
Storage The product should be stored at -80°C. Please do not repeated freeze-thaw cycles.
ACCN NM_018654
Protein Families GPCR
Protein Pathways
MW The human full length GPRC5D Protein has a MW of 38.6 kDa
Protein Summary The protein encoded by this gene is a member of the G protein-coupled receptor family. Recent studies demonstrate that GPRC5D is expressed on malignant bone marrow plasma cells, whereas normal tissue expression is limited to the hair follicle. It may represent a potential target for effector-cell–mediated therapy to treat plasma-cell disorders like MM.
UniProt ID Q9NZD1
Delivery In Stock
Images

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Figure 1. Elisa plates were added with Flag Tag GPRC5D-Nanodisc (0.5μg/per well) on an anti-Flag monoclonal antibody pre-coated (0.5μg/per well) plate. Serial diluted anti-GPRC5D monoclonal antibody (DME100090) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-GPRC5D monoclonal antibody binding with GPRC5D-Nanodisc is 32.86ng/ml.


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Figure 2. Human GPRC5D-Nanodisc, Flag Tag on SDS-PAGE


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