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Human CCR4 full length protein-VLP

产品概述
Catalog Number FLP100015
package 50 μg ¥8000.00 ; 100 μg ¥10800.00
Description Human CCR4 full length protein-VLP
Expression Host HEK293
Symbol CCR4
ORF Size 1080 bp
Formulation Supplied in 1xPBS (pH 7.4)
Storage The product should be stored at -80°C. Please do not repeated freeze-thaw cycles.
ACCN NM_005508
Protein Families GPCR
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
MW The human full length CCR4 Protein has a MW of 41.4 kDa
Protein Summary The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
UniProt ID P51679
Delivery In Stock
Images

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Figure 1. Elisa plates were pre-coated with 0.5μg/per well purified human CCR4 full length VLP. Serial diluted anti-CCR4 monoclonal antibody (BME100086) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CCR4 monoclonal antibody binding with CCR4 full length VLP is 856.2ng/ml.

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