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18062749453
Human CB1 full length protein-MNP
| Catalog Number | FLP100009 |
|---|---|
| package | 50 μg ￥8000.00 ; 100 μg ￥10800.00 |
| Description | Human CB1 full length protein membrane nanoparticles (MNPs) |
| Expression Host | HEK293 |
| Symbol | CNR1 |
| ORF Size | 1416 bp |
| Formulation | Supplied in 1xPBS (pH 7.4) |
| Storage | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
| ACCN | NM_016083 |
| Protein Families | GPCR |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| MW | The human full length CB1 Protein has a MW of 52.7 kDa |
| Protein Summary | The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. |
| UniProt ID | P21554 |
| Delivery | In Stock |
| Images |
Figure 1. Elisa plates were pre-coated with 0.5μg/per well purified human CB1 full length membrane nanoparticles. Serial diluted anti-CB1 monoclonal antibody (DME100144) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CB1 monoclonal antibody binding with CB1 full length membrane nanoparticles is 439.6ng/ml.
Figure 2. FACS analysis of CB1 MNPs A. Negative Control 1: CB1 full length membrane nanoparticles samples were stained only with Goat anti-human lgG 488 secondary antibody. B. Negative Control 2: Control membrane nanoparticles samples were stained with anti-CB1 antibody (BME100049) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody. C. Negative Control 3: CB1 full length membrane nanoparticles samples were stained with anti-CCR8 antibody (an irrelevant antibody) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody. D. CB1 full length membrane nanoparticles samples were stained with anti-CB1 antibody (BME100049) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody. |
| 说明书 | 立即下载 | COA | 立即下载 |
|---|---|---|---|
| MSDS | 立即下载 | ||
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