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Human PD-1 Protein, His tag

产品概述
Catalog Number PME100461
Package 10 μg ¥600.00 ; 50 μg ¥2300.00 ; 100 μg ¥3400.00
Description Recombinant human PD-1 protein with C-terminal 6×His tag
Synonyms PDCD1, PD1, CD279, SLEB2
Delivery In Stock
Uniprot ID Q15116
Expression Host HEK293
Tag C-6×His tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 16.8 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
Usage Research use only
Images

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Figure 1. Human PD-1 Protein, His Tag on SDS-PAGE under reducing condition.

Background This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
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