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Human 5T4 Protein, His Tag

产品概述
Catalog Number PME100123
Package 10 μg ¥600.00 ; 50 μg ¥2300.00 ; 100 μg ¥3400.00
Description Recombinant Human 5T4 Protein with C-terminal 6×His tag
Synonyms 5T4, 5T4AG, M6P1, WAIF1
Delivery In Stock
Uniprot ID Q13641
Expression Host HEK293
Tag C-6×His tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 36.1 kDa after removal of the signal peptide.The apparent molecular mass of 5T4-His is approximately 55-70 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
Usage Research use only
Images

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Figure 1. Human 5T4 Protein, His Tag on SDS-PAGE under reducing condition.

Background This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.
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