Human CD130 Protein, hFc Tag
| Catalog Number | PME100811 |
|---|---|
| Package | 10 μg ￥600.00 ; 50 μg ￥2400.00 ; 100 μg ￥3600.00 |
| Description | Recombinant human CD130 protein with C-terminal human Fc tag |
| Synonyms | CD130, CDW130, GP130, IL-6RB |
| Delivery | Under development |
| Uniprot ID | P40189 |
| Expression Host | HEK293 |
| Tag | C-Human Fc |
| Molecular Characterization |
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| Molecular Weight | The protein has a predicted molecular mass of 91.19 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
| Usage | Research use only |
| Images |
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| Background | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. |
| 说明书 | 立即下载 | COA | 立即下载 |
|---|---|---|---|
| MSDS | 立即下载 | ||
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