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Human CD3D Protein, His Tag

产品概述
Catalog Number PME100800
Package 10 μg ¥600.00 ; 50 μg ¥2400.00 ; 100 μg ¥3600.00
Description Recombinant human CD3D protein with C-terminal 6×His tag
Synonyms T-cell surface glycoprotein CD3 delta chain,T-cell receptor T3 delta chain
Delivery In Stock
Uniprot ID P04234
Expression Host HEK293
Tag C-6×His tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 10.4 kDa after removal of the signal peptide. The apparent molecular mass of CD3D-His is approximately 15-25 kDa due to glycosylation.
Purity The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
Usage Research use only
Images

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Figure 1. Human CD3D Protein, His Tag on SDS-PAGE under reducing condition.

Background The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
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