Human TGFBR1 Protein, hFc Tag
Catalog Number | PME100103 |
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Package | 10 μg ¥600.00 ; 50 μg ¥2300.00 ; 100 μg ¥3400.00 |
Description | Recombinant human TGFBR1 Protein with N-Human Fc tag |
Synonyms | AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, tbetaR-I, TBR-i, TBRI, TGFR-1 |
Delivery | In Stock |
Uniprot ID | P36897 |
Expression Host | HEK293 |
Tag | N-Human Fc tag |
Molecular Characterization |
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Molecular Weight | The protein has a predicted molecular mass of 36.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-TGFBR1 is approximately 40-53 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Storage | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Usage | Research use only |
Images |
Figure 1. Human TGFBR1 Protein, hFc Tag on SDS-PAGE under reducing condition. |
Background | The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. |
说明书 | 立即下载 | COA | 立即下载 |
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MSDS | 立即下载 |